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This maxi vertical gel box combines convenient ease of use features with high resolution separations. Simple set up using ultra soft silicone seals guarantees trouble free glass plate loading and gel casting. Dual gaskets on the gel running insert, along with notched and plain glass plates, ensure leak proof gel running. Rapid set up cooling retains resolution in extended separations and also saves on buffer volume without affecting run quality. Glass plates reduce breakage and have bonded spacers for added convenience.